Interference with TGFβ1-Mediated Inflammation and Fibrosis Underlies Reno-Protective Effects of the...
Interference with TGFβ1-Mediated Inflammation and Fibrosis Underlies Reno-Protective Effects of the CB1 Receptor Neutral Antagonists AM6545 and AM4113 in a Rat Model of Metabolic Syndrome
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Switzerland: MDPI AG
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Language
English
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Switzerland: MDPI AG
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The role of cannabinoid receptors in nephropathy is gaining much attention. This study investigated the effects of two neutral CB1 receptor antagonists, AM6545 and AM4113, on nephropathy associated with metabolic syndrome (MetS). MetS was induced in rats by high-fructose high-salt feeding for 12 weeks. AM6545, the peripheral silent antagonist and A...
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Full title
Interference with TGFβ1-Mediated Inflammation and Fibrosis Underlies Reno-Protective Effects of the CB1 Receptor Neutral Antagonists AM6545 and AM4113 in a Rat Model of Metabolic Syndrome
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TN_cdi_doaj_primary_oai_doaj_org_article_92c098f9897b48249f94b5e62c63f2c0
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_92c098f9897b48249f94b5e62c63f2c0
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ISSN
1420-3049
E-ISSN
1420-3049
DOI
10.3390/molecules26040866
