Intravitreal delivery of NMO-IgG causes primary retinal damage in the absence of optic nerve injury
Intravitreal delivery of NMO-IgG causes primary retinal damage in the absence of optic nerve injury
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Author / Creator
Chen, Biyue , Zhou, Huanfen , Sun, Mingming , Yang, Wanqun , Li, Qianqian , Yang, Kaishu , Song, Honglu , Xu, Quangang , Xu, Xintong , Li, Yuyu , Yu, Yanyan , Wei, Shihui and Chen, Tingjun
Publisher
England: BioMed Central Ltd
Journal title
Language
English
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Publisher
England: BioMed Central Ltd
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Scope and Contents
Contents
Neuromyelitis Optica (NMO) is a neuroimmune disorder primarily driven by autoantibodies against aquaporin 4 (AQP4), known as NMO-IgG. Although the mechanisms underlying NMO-IgG-induced retinopathy are not fully understood, the high expression of AQP4 in retinal Müller cells suggests a direct interaction that may trigger inflammatory processes in th...
Alternative Titles
Full title
Intravitreal delivery of NMO-IgG causes primary retinal damage in the absence of optic nerve injury
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Record Identifier
TN_cdi_doaj_primary_oai_doaj_org_article_92fa02b421924e099322d67586ca7990
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_92fa02b421924e099322d67586ca7990
Other Identifiers
ISSN
1742-2094
E-ISSN
1742-2094
DOI
10.1186/s12974-025-03380-z
