Bone marrow mesenchymal stem cells promote remyelination in spinal cord by driving oligodendrocyte p...
Bone marrow mesenchymal stem cells promote remyelination in spinal cord by driving oligodendrocyte progenitor cell differentiation via TNFα/RelB-Hes1 pathway: a rat model study of 2,5-hexanedione-induced neurotoxicity
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Author / Creator
Li, Shuangyue , Guan, Huai , Zhang, Yan , Li, Sheng , Li, Kaixin , Hu, Shuhai , Zuo, Enjun , Zhang, Cong , Zhang, Xin , Gong, Guanyu , Wang, Ruoyu and Piao, Fengyuan
Publisher
London: BioMed Central
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Language
English
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Publisher
London: BioMed Central
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Contents
Background N-hexane, with its metabolite 2,5-hexanedine (HD), is an industrial hazardous material. Chronic hexane exposure causes segmental demyelination in the peripheral nerves, and high-dose intoxication may also affect central nervous system. Demyelinating conditions are difficult to treat and stem cell therapy using bone marrow mesenchymal ste...
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Full title
Bone marrow mesenchymal stem cells promote remyelination in spinal cord by driving oligodendrocyte progenitor cell differentiation via TNFα/RelB-Hes1 pathway: a rat model study of 2,5-hexanedione-induced neurotoxicity
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Record Identifier
TN_cdi_doaj_primary_oai_doaj_org_article_92fa37cc93ed488ab703e0058ab4e83e
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_92fa37cc93ed488ab703e0058ab4e83e
Other Identifiers
ISSN
1757-6512
E-ISSN
1757-6512
DOI
10.1186/s13287-021-02518-z
