Modulating mitofusins to control mitochondrial function and signaling
Modulating mitofusins to control mitochondrial function and signaling
About this item
Full title
Author / Creator
Zacharioudakis, Emmanouil , Agianian, Bogos , Kumar MV, Vasantha , Biris, Nikolaos , Garner, Thomas P. , Rabinovich-Nikitin, Inna , Ouchida, Amanda T. , Margulets, Victoria , Nordstrøm, Lars Ulrik , Riley, Joel S. , Dolgalev, Igor , Chen, Yun , Wittig, Andre J. H. , Pekson, Ryan , Mathew, Chris , Wei, Peter , Tsirigos, Aristotelis , Tait, Stephen W. G. , Kirshenbaum, Lorrie A. , Kitsis, Richard N. and Gavathiotis, Evripidis
Publisher
London: Nature Publishing Group UK
Journal title
Language
English
Formats
Publication information
Publisher
London: Nature Publishing Group UK
Subjects
More information
Scope and Contents
Contents
Mitofusins reside on the outer mitochondrial membrane and regulate mitochondrial fusion, a physiological process that impacts diverse cellular processes. Mitofusins are activated by conformational changes and subsequently oligomerize to enable mitochondrial fusion. Here, we identify small molecules that directly increase or inhibit mitofusins activ...
Alternative Titles
Full title
Modulating mitofusins to control mitochondrial function and signaling
Authors, Artists and Contributors
Author / Creator
Agianian, Bogos
Kumar MV, Vasantha
Biris, Nikolaos
Garner, Thomas P.
Rabinovich-Nikitin, Inna
Ouchida, Amanda T.
Margulets, Victoria
Nordstrøm, Lars Ulrik
Riley, Joel S.
Dolgalev, Igor
Chen, Yun
Wittig, Andre J. H.
Pekson, Ryan
Mathew, Chris
Wei, Peter
Tsirigos, Aristotelis
Tait, Stephen W. G.
Kirshenbaum, Lorrie A.
Kitsis, Richard N.
Gavathiotis, Evripidis
Identifiers
Primary Identifiers
Record Identifier
TN_cdi_doaj_primary_oai_doaj_org_article_92fc0c999e924a40a5e55d06aabc43db
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_92fc0c999e924a40a5e55d06aabc43db
Other Identifiers
ISSN
2041-1723
E-ISSN
2041-1723
DOI
10.1038/s41467-022-31324-1
