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Functional role of Tet-mediated RNA hydroxymethylcytosine in mouse ES cells and during differentiati...

Functional role of Tet-mediated RNA hydroxymethylcytosine in mouse ES cells and during differentiati...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_9305faa1ca904cdba667b6f5f1a6c75f

Functional role of Tet-mediated RNA hydroxymethylcytosine in mouse ES cells and during differentiation

About this item

Full title

Functional role of Tet-mediated RNA hydroxymethylcytosine in mouse ES cells and during differentiation

Publisher

London: Nature Publishing Group UK

Journal title

Nature communications, 2020-10, Vol.11 (1), p.4956-4956, Article 4956

Language

English

Formats

Publication information

Publisher

London: Nature Publishing Group UK

More information

Scope and Contents

Contents

Tet-enzyme-mediated 5-hydroxymethylation of cytosines in DNA plays a crucial role in mouse embryonic stem cells (ESCs). In RNA also, 5-hydroxymethylcytosine (5hmC) has recently been evidenced, but its physiological roles are still largely unknown. Here we show the contribution and function of this mark in mouse ESCs and differentiating embryoid bod...

Alternative Titles

Full title

Functional role of Tet-mediated RNA hydroxymethylcytosine in mouse ES cells and during differentiation

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_doaj_primary_oai_doaj_org_article_9305faa1ca904cdba667b6f5f1a6c75f

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_9305faa1ca904cdba667b6f5f1a6c75f

Other Identifiers

ISSN

2041-1723

E-ISSN

2041-1723

DOI

10.1038/s41467-020-18729-6

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