Functional role of Tet-mediated RNA hydroxymethylcytosine in mouse ES cells and during differentiati...
Functional role of Tet-mediated RNA hydroxymethylcytosine in mouse ES cells and during differentiation
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Author / Creator
Lan, Jie , Rajan, Nicholas , Bizet, Martin , Penning, Audrey , Singh, Nitesh K. , Guallar, Diana , Calonne, Emilie , Li Greci, Andrea , Bonvin, Elise , Deplus, Rachel , Hsu, Phillip J. , Nachtergaele, Sigrid , Ma, Chengjie , Song, Renhua , Fuentes-Iglesias, Alejandro , Hassabi, Bouchra , Putmans, Pascale , Mies, Frédérique , Menschaert, Gerben , Wong, Justin J. L. , Wang, Jianlong , Fidalgo, Miguel , Yuan, Bifeng and Fuks, François
Publisher
London: Nature Publishing Group UK
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Language
English
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Publisher
London: Nature Publishing Group UK
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Contents
Tet-enzyme-mediated 5-hydroxymethylation of cytosines in DNA plays a crucial role in mouse embryonic stem cells (ESCs). In RNA also, 5-hydroxymethylcytosine (5hmC) has recently been evidenced, but its physiological roles are still largely unknown. Here we show the contribution and function of this mark in mouse ESCs and differentiating embryoid bod...
Alternative Titles
Full title
Functional role of Tet-mediated RNA hydroxymethylcytosine in mouse ES cells and during differentiation
Authors, Artists and Contributors
Author / Creator
Rajan, Nicholas
Bizet, Martin
Penning, Audrey
Singh, Nitesh K.
Guallar, Diana
Calonne, Emilie
Li Greci, Andrea
Bonvin, Elise
Deplus, Rachel
Hsu, Phillip J.
Nachtergaele, Sigrid
Ma, Chengjie
Song, Renhua
Fuentes-Iglesias, Alejandro
Hassabi, Bouchra
Putmans, Pascale
Mies, Frédérique
Menschaert, Gerben
Wong, Justin J. L.
Wang, Jianlong
Fidalgo, Miguel
Yuan, Bifeng
Fuks, François
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Primary Identifiers
Record Identifier
TN_cdi_doaj_primary_oai_doaj_org_article_9305faa1ca904cdba667b6f5f1a6c75f
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_9305faa1ca904cdba667b6f5f1a6c75f
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ISSN
2041-1723
E-ISSN
2041-1723
DOI
10.1038/s41467-020-18729-6