SCALE method for single-cell ATAC-seq analysis via latent feature extraction
SCALE method for single-cell ATAC-seq analysis via latent feature extraction
About this item
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Author / Creator
Xiong, Lei , Xu, Kui , Tian, Kang , Shao, Yanqiu , Tang, Lei , Gao, Ge , Zhang, Michael , Jiang, Tao and Zhang, Qiangfeng Cliff
Publisher
London: Nature Publishing Group UK
Journal title
Language
English
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Publication information
Publisher
London: Nature Publishing Group UK
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Scope and Contents
Contents
Single-cell ATAC-seq (scATAC-seq) profiles the chromatin accessibility landscape at single cell level, thus revealing cell-to-cell variability in gene regulation. However, the high dimensionality and sparsity of scATAC-seq data often complicate the analysis. Here, we introduce a method for analyzing scATAC-seq data, called Single-Cell ATAC-seq anal...
Alternative Titles
Full title
SCALE method for single-cell ATAC-seq analysis via latent feature extraction
Authors, Artists and Contributors
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Record Identifier
TN_cdi_doaj_primary_oai_doaj_org_article_9307133826f6483aacbf4da911ec0cc4
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_9307133826f6483aacbf4da911ec0cc4
Other Identifiers
ISSN
2041-1723
E-ISSN
2041-1723
DOI
10.1038/s41467-019-12630-7
