Perlecan, a candidate gene for the CAPB locus, regulates prostate cancer cell growth via the Sonic H...
Perlecan, a candidate gene for the CAPB locus, regulates prostate cancer cell growth via the Sonic Hedgehog pathway
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England: BioMed Central Ltd
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English
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England: BioMed Central Ltd
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Genetic studies associated the CAPB locus with familial risk of brain and prostate cancers. We have identified HSPG2 (Perlecan) as a candidate gene for CAPB. Previously we have linked Perlecan to Hedgehog signaling in Drosophila. More recently, we have demonstrated the importance of Hedgehog signaling in humans for advanced prostate cancer.
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Perlecan, a candidate gene for the CAPB locus, regulates prostate cancer cell growth via the Sonic Hedgehog pathway
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TN_cdi_doaj_primary_oai_doaj_org_article_9330f273ecaa4e7d90f0c57c03080fb7
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_9330f273ecaa4e7d90f0c57c03080fb7
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ISSN
1476-4598
E-ISSN
1476-4598
DOI
10.1186/1476-4598-5-9
