Synthetic Retinoid Kills Drug‐Resistant Cancer Stem Cells via Inducing RARγ‐Translocation‐Mediated T...
Synthetic Retinoid Kills Drug‐Resistant Cancer Stem Cells via Inducing RARγ‐Translocation‐Mediated Tension Reduction and Chromatin Decondensation
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Author / Creator
Zhang, Yao , Dong, Qi , An, Quanlin , Zhang, Chumei , Mohagheghian, Erfan , Niu, Bing , Qi, Feng , Wei, Fuxiang , Chen, Sihan , Chen, Xinman , Wang, Anqi , Cao, Xin , Wang, Ning and Chen, Junwei
Publisher
Germany: John Wiley & Sons, Inc
Journal title
Language
English
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Publication information
Publisher
Germany: John Wiley & Sons, Inc
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Scope and Contents
Contents
A recently developed synthetic retinoid abrogates proliferation and induces apoptosis of drug‐resistant malignant‐cancer‐stem‐cell‐like cells. However, the underlying mechanisms of how the synthetic retinoid induces cancer‐stem‐cell‐like cell tumor‐repopulating cell (TRC) apoptosis are elusive. Here, it is shown that although the retinoid and conve...
Alternative Titles
Full title
Synthetic Retinoid Kills Drug‐Resistant Cancer Stem Cells via Inducing RARγ‐Translocation‐Mediated Tension Reduction and Chromatin Decondensation
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Record Identifier
TN_cdi_doaj_primary_oai_doaj_org_article_93477889198c45418e30810334a96d1f
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_93477889198c45418e30810334a96d1f
Other Identifiers
ISSN
2198-3844
E-ISSN
2198-3844
DOI
10.1002/advs.202203173