Synergistic antitumor activity of pan-PI3K inhibition and immune checkpoint blockade in bladder canc...
Synergistic antitumor activity of pan-PI3K inhibition and immune checkpoint blockade in bladder cancer
About this item
Full title
Author / Creator
Publisher
England: BMJ Publishing Group Ltd
Journal title
Language
English
Formats
Publication information
Publisher
England: BMJ Publishing Group Ltd
Subjects
More information
Scope and Contents
Contents
BackgroundImmune checkpoint blockade (ICB) induces durable response in approximately 20% of patients with advanced bladder urothelial cancer (aUC). Over 50% of aUCs harbor genomic alterations along the phosphoinositide 3-kinase (PI3K) pathway. The goal of this project was to determine the synergistic effects and mechanisms of action of PI3K inhibit...
Alternative Titles
Full title
Synergistic antitumor activity of pan-PI3K inhibition and immune checkpoint blockade in bladder cancer
Authors, Artists and Contributors
Identifiers
Primary Identifiers
Record Identifier
TN_cdi_doaj_primary_oai_doaj_org_article_934d422d19464781b6e424dfea9fbd98
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_934d422d19464781b6e424dfea9fbd98
Other Identifiers
ISSN
2051-1426
E-ISSN
2051-1426
DOI
10.1136/jitc-2021-002917
