SLITRK2 variants associated with neurodevelopmental disorders impair excitatory synaptic function an...
SLITRK2 variants associated with neurodevelopmental disorders impair excitatory synaptic function and cognition in mice
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Author / Creator
El Chehadeh, Salima , Han, Kyung Ah , Kim, Dongwook , Jang, Gyubin , Bakhtiari, Somayeh , Lim, Dongseok , Kim, Hee Young , Kim, Jinhu , Kim, Hyeonho , Wynn, Julia , Chung, Wendy K. , Vitiello, Giuseppina , Cutcutache, Ioana , Page, Matthew , Gecz, Jozef , Harper, Kelly , Han, Ah-reum , Kim, Ho Min , Wessels, Marja , Bayat, Allan , Jaén, Alberto Fernández , Selicorni, Angelo , Maitz, Silvia , de Brouwer, Arjan P. M. , Silfhout, Anneke Vulto-van , Armstrong, Martin , Symonds, Joseph , Küry, Sébastien , Isidor, Bertrand , Cogné, Benjamin , Nizon, Mathilde , Feger, Claire , Muller, Jean , Torti, Erin , Grange, Dorothy K. , Willems, Marjolaine , Kruer, Michael C. , Ko, Jaewon , Piton, Amélie and Um, Ji Won
Publisher
London: Nature Publishing Group UK
Journal title
Language
English
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Publication information
Publisher
London: Nature Publishing Group UK
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More information
Scope and Contents
Contents
SLITRK2 is a single-pass transmembrane protein expressed at postsynaptic neurons that regulates neurite outgrowth and excitatory synapse maintenance. In the present study, we report on rare variants (one nonsense and six missense variants) in
SLITRK2
on the X chromosome identified by exome sequencing in individuals with neurodevelopmental dis...
Alternative Titles
Full title
SLITRK2 variants associated with neurodevelopmental disorders impair excitatory synaptic function and cognition in mice
Authors, Artists and Contributors
Author / Creator
Han, Kyung Ah
Kim, Dongwook
Jang, Gyubin
Bakhtiari, Somayeh
Lim, Dongseok
Kim, Hee Young
Kim, Jinhu
Kim, Hyeonho
Wynn, Julia
Chung, Wendy K.
Vitiello, Giuseppina
Cutcutache, Ioana
Page, Matthew
Gecz, Jozef
Harper, Kelly
Han, Ah-reum
Kim, Ho Min
Wessels, Marja
Bayat, Allan
Jaén, Alberto Fernández
Selicorni, Angelo
Maitz, Silvia
de Brouwer, Arjan P. M.
Silfhout, Anneke Vulto-van
Armstrong, Martin
Symonds, Joseph
Küry, Sébastien
Isidor, Bertrand
Cogné, Benjamin
Nizon, Mathilde
Feger, Claire
Muller, Jean
Torti, Erin
Grange, Dorothy K.
Willems, Marjolaine
Kruer, Michael C.
Ko, Jaewon
Piton, Amélie
Um, Ji Won
Identifiers
Primary Identifiers
Record Identifier
TN_cdi_doaj_primary_oai_doaj_org_article_939b1e803648458f978aa0c525329996
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_939b1e803648458f978aa0c525329996
Other Identifiers
ISSN
2041-1723
E-ISSN
2041-1723
DOI
10.1038/s41467-022-31566-z
