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Upper and Lower Motor Neuron Degenerations Are Somatotopically Related and Temporally Ordered in the...

Upper and Lower Motor Neuron Degenerations Are Somatotopically Related and Temporally Ordered in the...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_93db53e0b6864c3fbde7d3d58396af1b

Upper and Lower Motor Neuron Degenerations Are Somatotopically Related and Temporally Ordered in the Sod1 Mouse Model of Amyotrophic Lateral Sclerosis

About this item

Full title

Upper and Lower Motor Neuron Degenerations Are Somatotopically Related and Temporally Ordered in the Sod1 Mouse Model of Amyotrophic Lateral Sclerosis

Publisher

Switzerland: MDPI AG

Journal title

Brain sciences, 2021-03, Vol.11 (3), p.369

Language

English

Formats

Publication information

Publisher

Switzerland: MDPI AG

More information

Scope and Contents

Contents

Amyotrophic lateral sclerosis (ALS) is a devastating and fatal neurodegenerative disease arising from the combined degeneration of upper motor neurons (UMN) in the motor cortex, and lower motor neurons (LMN) in the brainstem and spinal cord. This dual impairment raises two major questions: (i) are the degenerations of these two neuronal populations...

Alternative Titles

Full title

Upper and Lower Motor Neuron Degenerations Are Somatotopically Related and Temporally Ordered in the Sod1 Mouse Model of Amyotrophic Lateral Sclerosis

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_doaj_primary_oai_doaj_org_article_93db53e0b6864c3fbde7d3d58396af1b

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_93db53e0b6864c3fbde7d3d58396af1b

Other Identifiers

ISSN

2076-3425

E-ISSN

2076-3425

DOI

10.3390/brainsci11030369

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