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Heterocycle-containing tranylcypromine derivatives endowed with high anti-LSD1 activity

Heterocycle-containing tranylcypromine derivatives endowed with high anti-LSD1 activity

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_93fcd4f9950b49e69e71b43501b4fcde

Heterocycle-containing tranylcypromine derivatives endowed with high anti-LSD1 activity

About this item

Full title

Heterocycle-containing tranylcypromine derivatives endowed with high anti-LSD1 activity

Publisher

England: Taylor & Francis

Journal title

Journal of enzyme inhibition and medicinal chemistry, 2022-12, Vol.37 (1), p.973-985

Language

English

Formats

Publication information

Publisher

England: Taylor & Francis

More information

Scope and Contents

Contents

As regioisomers/bioisosteres of 1a, a 4-phenylbenzamide tranylcypromine (TCP) derivative previously disclosed by us, we report here the synthesis and biological evaluation of some (hetero)arylbenzoylamino TCP derivatives 1b-6, in which the 4-phenyl moiety of 1a was shifted at the benzamide C3 position or replaced by 2- or 3-furyl, 2- or 3-thienyl,...

Alternative Titles

Full title

Heterocycle-containing tranylcypromine derivatives endowed with high anti-LSD1 activity

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_doaj_primary_oai_doaj_org_article_93fcd4f9950b49e69e71b43501b4fcde

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_93fcd4f9950b49e69e71b43501b4fcde

Other Identifiers

ISSN

1475-6366

E-ISSN

1475-6374

DOI

10.1080/14756366.2022.2052869

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