Synthesis and Antiviral Activity of Novel 1,3,4-Thiadiazole Inhibitors of DDX3X
Synthesis and Antiviral Activity of Novel 1,3,4-Thiadiazole Inhibitors of DDX3X
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Switzerland: MDPI AG
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Language
English
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Publisher
Switzerland: MDPI AG
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The human ATPase/RNA helicase X-linked DEAD-box polypeptide 3 (DDX3X) emerged as a novel therapeutic target in the fight against both infectious diseases and cancer. Herein, a new family of DDX3X inhibitors was designed, synthesized, and tested for its inhibitory action on the ATPase activity of the enzyme. The potential use of the most promising d...
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Full title
Synthesis and Antiviral Activity of Novel 1,3,4-Thiadiazole Inhibitors of DDX3X
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TN_cdi_doaj_primary_oai_doaj_org_article_9403db9a6536463ab27126f849bbc5c4
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_9403db9a6536463ab27126f849bbc5c4
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ISSN
1420-3049
E-ISSN
1420-3049
DOI
10.3390/molecules24213988
