Hepatocellular carcinoma patients with high circulating cytotoxic T cells and intra-tumoral immune s...
Hepatocellular carcinoma patients with high circulating cytotoxic T cells and intra-tumoral immune signature benefit from pembrolizumab: results from a single-arm phase 2 trial
About this item
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Author / Creator
Hong, Jung Yong , Cho, Hee Jin , Sa, Jason K. , Liu, Xiaoqiao , Ha, Sang Yun , Lee, Taehyang , Kim, Hajung , Kang, Wonseok , Sinn, Dong Hyun , Gwak, Geum-Youn , Choi, Moon Seok , Lee, Joon Hyeok , Koh, Kwang Cheol , Paik, Seung Woon , Park, Hee Chul , Kang, Tae Wook , Rhim, Hyunchul , Lee, Su Jin , Cristescu, Razvan , Lee, Jeeyun , Paik, Yong Han and Lim, Ho Yeong
Publisher
England: BioMed Central Ltd
Journal title
Language
English
Formats
Publication information
Publisher
England: BioMed Central Ltd
Subjects
More information
Scope and Contents
Contents
A limited number of studies have characterized genomic properties of hepatocellular carcinoma (HCC) patients in response to anti-PD-1 immunotherapy.
Herein, we performed comprehensive molecular characterization of immediate (D-42 to D-1) pre-treatment tumor biopsy specimens from 60 patients with sorafenib-failed HCC in a single-arm prospective p...
Alternative Titles
Full title
Hepatocellular carcinoma patients with high circulating cytotoxic T cells and intra-tumoral immune signature benefit from pembrolizumab: results from a single-arm phase 2 trial
Authors, Artists and Contributors
Author / Creator
Cho, Hee Jin
Sa, Jason K.
Liu, Xiaoqiao
Ha, Sang Yun
Lee, Taehyang
Kim, Hajung
Kang, Wonseok
Sinn, Dong Hyun
Gwak, Geum-Youn
Choi, Moon Seok
Lee, Joon Hyeok
Koh, Kwang Cheol
Paik, Seung Woon
Park, Hee Chul
Kang, Tae Wook
Rhim, Hyunchul
Lee, Su Jin
Cristescu, Razvan
Lee, Jeeyun
Paik, Yong Han
Lim, Ho Yeong
Identifiers
Primary Identifiers
Record Identifier
TN_cdi_doaj_primary_oai_doaj_org_article_9436a920f67a4275b778a98aec3608cb
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_9436a920f67a4275b778a98aec3608cb
Other Identifiers
ISSN
1756-994X
E-ISSN
1756-994X
DOI
10.1186/s13073-021-00995-8
