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scFv biofunctionalized nanoparticles to effective and safe targeting of CEA-expressing colorectal ca...

scFv biofunctionalized nanoparticles to effective and safe targeting of CEA-expressing colorectal ca...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_944965b549244896b8d04d9d5315af44

scFv biofunctionalized nanoparticles to effective and safe targeting of CEA-expressing colorectal cancer cells

About this item

Full title

scFv biofunctionalized nanoparticles to effective and safe targeting of CEA-expressing colorectal cancer cells

Publisher

London: BioMed Central Ltd

Journal title

Journal of nanobiotechnology, 2023-10, Vol.21 (1), p.1-357, Article 357

Language

English

Formats

Publication information

Publisher

London: BioMed Central Ltd

More information

Scope and Contents

Contents

Colorectal cancer (CRC) is one of the deadliest cancers worldwide, with the 5 year survival rate in metastatic cases limited to 12%. The design of targeted and effective therapeutics remains a major unmet clinical need in CRC treatment. Carcinoembryonic antigen (CEA), a glycoprotein overexpressed in most colorectal tumors, may constitute a promisin...

Alternative Titles

Full title

scFv biofunctionalized nanoparticles to effective and safe targeting of CEA-expressing colorectal cancer cells

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_doaj_primary_oai_doaj_org_article_944965b549244896b8d04d9d5315af44

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_944965b549244896b8d04d9d5315af44

Other Identifiers

ISSN

1477-3155

E-ISSN

1477-3155

DOI

10.1186/s12951-023-02126-4

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