scFv biofunctionalized nanoparticles to effective and safe targeting of CEA-expressing colorectal ca...
scFv biofunctionalized nanoparticles to effective and safe targeting of CEA-expressing colorectal cancer cells
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Publisher
London: BioMed Central Ltd
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Language
English
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Publisher
London: BioMed Central Ltd
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Contents
Colorectal cancer (CRC) is one of the deadliest cancers worldwide, with the 5 year survival rate in metastatic cases limited to 12%. The design of targeted and effective therapeutics remains a major unmet clinical need in CRC treatment. Carcinoembryonic antigen (CEA), a glycoprotein overexpressed in most colorectal tumors, may constitute a promisin...
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Full title
scFv biofunctionalized nanoparticles to effective and safe targeting of CEA-expressing colorectal cancer cells
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TN_cdi_doaj_primary_oai_doaj_org_article_944965b549244896b8d04d9d5315af44
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_944965b549244896b8d04d9d5315af44
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ISSN
1477-3155
E-ISSN
1477-3155
DOI
10.1186/s12951-023-02126-4