A Potential Role of RUNX2- RUNT Domain in Modulating the Expression of Genes Involved in Bone Metast...
A Potential Role of RUNX2- RUNT Domain in Modulating the Expression of Genes Involved in Bone Metastases: An In Vitro Study with Melanoma Cells
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Switzerland: MDPI AG
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English
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Switzerland: MDPI AG
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Ectopic expression of RUNX2 has been reported in several tumors. In melanoma cells, the RUNT domain of RUNX2 increases cell proliferation and migration. Due to the strong link between RUNX2 and skeletal development, we hypothesized that the RUNT domain may be involved in the modulation of mechanisms associated with melanoma bone metastasis. Therefo...
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Full title
A Potential Role of RUNX2- RUNT Domain in Modulating the Expression of Genes Involved in Bone Metastases: An In Vitro Study with Melanoma Cells
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TN_cdi_doaj_primary_oai_doaj_org_article_94861e385b224bbaa55d8086abaa378c
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_94861e385b224bbaa55d8086abaa378c
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ISSN
2073-4409
E-ISSN
2073-4409
DOI
10.3390/cells9030751
