Muscle pathology from stochastic low level DUX4 expression in an FSHD mouse model
Muscle pathology from stochastic low level DUX4 expression in an FSHD mouse model
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London: Nature Publishing Group UK
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English
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London: Nature Publishing Group UK
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Facioscapulohumeral muscular dystrophy is a slowly progressive but devastating myopathy caused by loss of repression of the transcription factor DUX4; however, DUX4 expression is very low, and protein has not been detected directly in patient biopsies. Efforts to model DUX4 myopathy in mice have foundered either in being too severe, or in lacking m...
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Muscle pathology from stochastic low level DUX4 expression in an FSHD mouse model
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TN_cdi_doaj_primary_oai_doaj_org_article_9516fa4c1ad1467299b0aa2dfdddf207
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_9516fa4c1ad1467299b0aa2dfdddf207
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ISSN
2041-1723
E-ISSN
2041-1723
DOI
10.1038/s41467-017-00730-1
