Statistical inference reveals the role of length, GC content, and local sequence in V(D)J nucleotide...
Statistical inference reveals the role of length, GC content, and local sequence in V(D)J nucleotide trimming
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England: eLife Sciences Publications Ltd
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English
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England: eLife Sciences Publications Ltd
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To appropriately defend against a wide array of pathogens, humans somatically generate highly diverse repertoires of B cell and T cell receptors (BCRs and TCRs) through a random process called V(D)J recombination. Receptor diversity is achieved during this process through both the combinatorial assembly of V(D)J-genes and the junctional deletion an...
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Statistical inference reveals the role of length, GC content, and local sequence in V(D)J nucleotide trimming
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TN_cdi_doaj_primary_oai_doaj_org_article_954f923ab0d24c51b54190fb2b2bfec9
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_954f923ab0d24c51b54190fb2b2bfec9
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ISSN
2050-084X
E-ISSN
2050-084X
DOI
10.7554/eLife.85145