Endothelial LRP1 regulates metabolic responses by acting as a co-activator of PPARγ
Endothelial LRP1 regulates metabolic responses by acting as a co-activator of PPARγ
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Publisher
London: Nature Publishing Group UK
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Language
English
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London: Nature Publishing Group UK
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Contents
Low-density lipoprotein receptor-related protein 1 (LRP1) regulates lipid and glucose metabolism in liver and adipose tissue. It is also involved in central nervous system regulation of food intake and leptin signalling. Here we demonstrate that endothelial Lrp1 regulates systemic energy homeostasis. Mice with endothelial-specific Lrp1 deletion dis...
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Endothelial LRP1 regulates metabolic responses by acting as a co-activator of PPARγ
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TN_cdi_doaj_primary_oai_doaj_org_article_9568598d8eac4446926e96a6f3554058
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_9568598d8eac4446926e96a6f3554058
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ISSN
2041-1723
E-ISSN
2041-1723
DOI
10.1038/ncomms14960
