Preparation, COX-2 Inhibition and Anticancer Activity of Sclerotiorin Derivatives
Preparation, COX-2 Inhibition and Anticancer Activity of Sclerotiorin Derivatives
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Author / Creator
Chen, Tao , Huang, Yun , Hong, Junxian , Wei, Xikang , Zeng, Fang , Li, Jialin , Ye, Geting , Yuan, Jie and Long, Yuhua
Publisher
Switzerland: MDPI AG
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Language
English
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Publisher
Switzerland: MDPI AG
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Contents
The latest research has indicated that anti-tumor agents with COX-2 inhibitory activity may benefit their anti-tumor efficiency. A series of sclerotiorin derivatives have been synthesized and screened for their cytotoxic activity against human lung cancer cells A549, breast cancer cells MDA-MB-435 using the MTT method. Among them, compounds 3, 7, 1...
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Full title
Preparation, COX-2 Inhibition and Anticancer Activity of Sclerotiorin Derivatives
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TN_cdi_doaj_primary_oai_doaj_org_article_956e526d086a40afbe92c0ca9d79eb31
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_956e526d086a40afbe92c0ca9d79eb31
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ISSN
1660-3397
E-ISSN
1660-3397
DOI
10.3390/md19010012