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PD-L1 signaling selectively regulates T cell lymphatic transendothelial migration

PD-L1 signaling selectively regulates T cell lymphatic transendothelial migration

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_95f1ec3c1b3240e0a0c30c1a91d6a299

PD-L1 signaling selectively regulates T cell lymphatic transendothelial migration

About this item

Full title

PD-L1 signaling selectively regulates T cell lymphatic transendothelial migration

Publisher

London: Nature Publishing Group UK

Journal title

Nature communications, 2022-04, Vol.13 (1), p.2176-15, Article 2176

Language

English

Formats

Publication information

Publisher

London: Nature Publishing Group UK

More information

Scope and Contents

Contents

Programmed death-1 (PD-1) and its ligand PD-L1 are checkpoint molecules which regulate immune responses. Little is known about their functions in T cell migration and there are contradictory data about their roles in regulatory T cell (Treg) function. Here we show activated Tregs and CD4 effector T cells (Teffs) use PD-1/PD-L1 and CD80/PD-L1, respe...

Alternative Titles

Full title

PD-L1 signaling selectively regulates T cell lymphatic transendothelial migration

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_doaj_primary_oai_doaj_org_article_95f1ec3c1b3240e0a0c30c1a91d6a299

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_95f1ec3c1b3240e0a0c30c1a91d6a299

Other Identifiers

ISSN

2041-1723

E-ISSN

2041-1723

DOI

10.1038/s41467-022-29930-0

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