A host defense peptide mimetic, brilacidin, potentiates caspofungin antifungal activity against huma...
A host defense peptide mimetic, brilacidin, potentiates caspofungin antifungal activity against human pathogenic fungi
About this item
Full title
Author / Creator
dos Reis, Thaila Fernanda , de Castro, Patrícia Alves , Bastos, Rafael Wesley , Pinzan, Camila Figueiredo , Souza, Pedro F. N. , Ackloo, Suzanne , Hossain, Mohammad Anwar , Drewry, David Harold , Alkhazraji, Sondus , Ibrahim, Ashraf S. , Jo, Hyunil , Lightfoot, Jorge D. , Adams, Emily M. , Fuller, Kevin K. , deGrado, William F. and Goldman, Gustavo H.
Publisher
London: Nature Publishing Group UK
Journal title
Language
English
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Publication information
Publisher
London: Nature Publishing Group UK
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Scope and Contents
Contents
Fungal infections cause more than 1.5 million deaths a year. Due to emerging antifungal drug resistance, novel strategies are urgently needed to combat life-threatening fungal diseases. Here, we identify the host defense peptide mimetic, brilacidin (BRI) as a synergizer with caspofungin (CAS) against CAS-sensitive and CAS-resistant isolates of
A...
Alternative Titles
Full title
A host defense peptide mimetic, brilacidin, potentiates caspofungin antifungal activity against human pathogenic fungi
Authors, Artists and Contributors
Author / Creator
de Castro, Patrícia Alves
Bastos, Rafael Wesley
Pinzan, Camila Figueiredo
Souza, Pedro F. N.
Ackloo, Suzanne
Hossain, Mohammad Anwar
Drewry, David Harold
Alkhazraji, Sondus
Ibrahim, Ashraf S.
Jo, Hyunil
Lightfoot, Jorge D.
Adams, Emily M.
Fuller, Kevin K.
deGrado, William F.
Goldman, Gustavo H.
Identifiers
Primary Identifiers
Record Identifier
TN_cdi_doaj_primary_oai_doaj_org_article_95f2a58a934d446abc7358a90c1dec91
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_95f2a58a934d446abc7358a90c1dec91
Other Identifiers
ISSN
2041-1723
E-ISSN
2041-1723
DOI
10.1038/s41467-023-37573-y