Shank and Zinc Mediate an AMPA Receptor Subunit Switch in Developing Neurons
Shank and Zinc Mediate an AMPA Receptor Subunit Switch in Developing Neurons
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Publisher
Switzerland: Frontiers Research Foundation
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Language
English
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Switzerland: Frontiers Research Foundation
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Contents
During development, pyramidal neurons undergo dynamic regulation of AMPA receptor (AMPAR) subunit composition and density to help drive synaptic plasticity and maturation. These normal developmental changes in AMPARs are particularly vulnerable to risk factors for Autism Spectrum Disorders (ASDs), which include loss or mutations of synaptic protein...
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Full title
Shank and Zinc Mediate an AMPA Receptor Subunit Switch in Developing Neurons
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TN_cdi_doaj_primary_oai_doaj_org_article_95f494fd563543b49d09449d0553c14b
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_95f494fd563543b49d09449d0553c14b
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ISSN
1662-5099
E-ISSN
1662-5099
DOI
10.3389/fnmol.2018.00405
