The Increased Dissolution and Oral Absorption of Itraconazole by Nanocrystals with an Endogenous Sma...
The Increased Dissolution and Oral Absorption of Itraconazole by Nanocrystals with an Endogenous Small-Molecule Surfactant as a Stabilizer
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Author / Creator
Chang, Sheng , Yang, Qiang , Liu, Jiahuan , Yin, Li , Han, Jihong , Zong, Lanlan and Pu, Xiaohui
Publisher
Switzerland: MDPI AG
Journal title
Language
English
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Publication information
Publisher
Switzerland: MDPI AG
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Scope and Contents
Contents
The aim of this study was to develop cholic-acid-stabilized itraconazole nanosuspensions (ITZ-Nanos) with the objective of enhancing drug dissolution and oral absorption. A laboratory-scale microprecipitation–high-pressure homogenization method was employed for the preparation of the ITZ-Nanos, while dynamic light scattering, transmission electron...
Alternative Titles
Full title
The Increased Dissolution and Oral Absorption of Itraconazole by Nanocrystals with an Endogenous Small-Molecule Surfactant as a Stabilizer
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Record Identifier
TN_cdi_doaj_primary_oai_doaj_org_article_9600efcf731a4227aed3c9ef37ffae43
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_9600efcf731a4227aed3c9ef37ffae43
Other Identifiers
ISSN
1420-3049
E-ISSN
1420-3049
DOI
10.3390/molecules29081769