Novel loci and biomedical consequences of iron homoeostasis variation
Novel loci and biomedical consequences of iron homoeostasis variation
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DBDS Genomic Consortium , FinnGen Consortium , Allara, Elias , Bell, Steven , Smith, Rebecca , Keene, Spencer J. , Gill, Dipender , Gaziano, Liam , Morselli Gysi, Deisy , Wang, Feiyi , Tragante, Vinicius , Mason, Amy , Karthikeyan, Savita , Lumbers, R. Thomas , Bonglack, Emmanuela , Ouwehand, Willem , Roberts, David J. , Dowsett, Joseph , Ostrowski, Sisse Rye , Larsen, Margit Hørup , Ullum, Henrik , Pedersen, Ole Birger , Brunak, Søren , Banasik, Karina , Erikstrup, Christian , Mitchell, Jonathan , Fuchsberger, Christian , Pattaro, Cristian , Pramstaller, Peter P. , Girelli, Domenico , Arvas, Mikko , Toivonen, Jarkko , Molnos, Sophie , Peters, Annette , Polasek, Ozren , Rudan, Igor , Hayward, Caroline , McDonnell, Ciara , Pirastu, Nicola , Wilson, James F. , van den Hurk, Katja , Quee, Franke , Ferrucci, Luigi , Bandinelli, Stefania , Tanaka, Toshiko , Girotto, Giorgia , Concas, Maria Pina , Pecori, Alessandro , Verweij, Niek , van der Harst, Pim , van de Vegte, Yordi J. , Kiemeney, Lambertus A. , Sweep, Fred C. , Galesloot, Tessel E. , Sulem, Patrick , Gudbjartsson, Daniel , Ferkingstad, Egil , Djousse, Luc , Cho, Kelly , Inouye, Michael , Burgess, Stephen , Benyamin, Beben , Oexle, Konrad , Swinkels, Dorine , Stefansson, Kari , Magnusson, Magnus , Ganna, Andrea , Gaziano, Michael , Ivey, Kerry , Danesh, John , Pereira, Alexandre , Wood, Angela M. , Butterworth, Adam S. and Di Angelantonio, Emanuele
Publisher
London: Nature Publishing Group UK
Journal title
Language
English
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Publisher
London: Nature Publishing Group UK
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Contents
Iron homoeostasis is tightly regulated, with hepcidin and soluble transferrin receptor (sTfR) playing significant roles. However, the genetic determinants of these traits and the biomedical consequences of iron homoeostasis variation are unclear. In a meta-analysis of 12 cohorts involving 91,675 participants, we found 43 genomic loci associated wit...
Alternative Titles
Full title
Novel loci and biomedical consequences of iron homoeostasis variation
Authors, Artists and Contributors
Author / Creator
FinnGen Consortium
Allara, Elias
Bell, Steven
Smith, Rebecca
Keene, Spencer J.
Gill, Dipender
Gaziano, Liam
Morselli Gysi, Deisy
Wang, Feiyi
Tragante, Vinicius
Mason, Amy
Karthikeyan, Savita
Lumbers, R. Thomas
Bonglack, Emmanuela
Ouwehand, Willem
Roberts, David J.
Dowsett, Joseph
Ostrowski, Sisse Rye
Larsen, Margit Hørup
Ullum, Henrik
Pedersen, Ole Birger
Brunak, Søren
Banasik, Karina
Erikstrup, Christian
Mitchell, Jonathan
Fuchsberger, Christian
Pattaro, Cristian
Pramstaller, Peter P.
Girelli, Domenico
Arvas, Mikko
Toivonen, Jarkko
Molnos, Sophie
Peters, Annette
Polasek, Ozren
Rudan, Igor
Hayward, Caroline
McDonnell, Ciara
Pirastu, Nicola
Wilson, James F.
van den Hurk, Katja
Quee, Franke
Ferrucci, Luigi
Bandinelli, Stefania
Tanaka, Toshiko
Girotto, Giorgia
Concas, Maria Pina
Pecori, Alessandro
Verweij, Niek
van der Harst, Pim
van de Vegte, Yordi J.
Kiemeney, Lambertus A.
Sweep, Fred C.
Galesloot, Tessel E.
Sulem, Patrick
Gudbjartsson, Daniel
Ferkingstad, Egil
Djousse, Luc
Cho, Kelly
Inouye, Michael
Burgess, Stephen
Benyamin, Beben
Oexle, Konrad
Swinkels, Dorine
Stefansson, Kari
Magnusson, Magnus
Ganna, Andrea
Gaziano, Michael
Ivey, Kerry
Danesh, John
Pereira, Alexandre
Wood, Angela M.
Butterworth, Adam S.
Di Angelantonio, Emanuele
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Primary Identifiers
Record Identifier
TN_cdi_doaj_primary_oai_doaj_org_article_9612bd28250149b99e442728bc5f20bf
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_9612bd28250149b99e442728bc5f20bf
Other Identifiers
ISSN
2399-3642
E-ISSN
2399-3642
DOI
10.1038/s42003-024-07115-3
