Stress fiber anisotropy contributes to force-mode dependent chromatin stretching and gene upregulati...
Stress fiber anisotropy contributes to force-mode dependent chromatin stretching and gene upregulation in living cells
About this item
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Author / Creator
Wei, Fuxiang , Xu, Xiangyu , Zhang, Cunyu , Liao, Yawen , Ji, Baohua and Wang, Ning
Publisher
London: Nature Publishing Group UK
Journal title
Language
English
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Publication information
Publisher
London: Nature Publishing Group UK
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Contents
Living cells and tissues experience various complex modes of forces that are important in physiology and disease. However, how different force modes impact gene expression is elusive. Here we apply local forces of different modes via a magnetic bead bound to the integrins on a cell and quantified cell stiffness, chromatin deformation, and
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Full title
Stress fiber anisotropy contributes to force-mode dependent chromatin stretching and gene upregulation in living cells
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TN_cdi_doaj_primary_oai_doaj_org_article_962d1725337f4e5b8e220adf785b2708
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_962d1725337f4e5b8e220adf785b2708
Other Identifiers
ISSN
2041-1723
E-ISSN
2041-1723
DOI
10.1038/s41467-020-18584-5
