Significance of the Tks4 scaffold protein in bone tissue homeostasis
Significance of the Tks4 scaffold protein in bone tissue homeostasis
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Author / Creator
Vas, Virag , Kovács, Tamás , Körmendi, Szandra , Bródy, Andrea , Kudlik, Gyöngyi , Szeder, Bálint , Mező, Diána , Kállai, Dóra , Koprivanacz, Kitti , Merő, Balázs L. , Dülk, Metta , Tóvári, József , Vajdovich, Péter , Şenel, Ş. Neslihan , Özcan, Ilknur , Helyes, Zsuzsanna , Dobó-Nagy, Csaba and Buday, László
Publisher
London: Nature Publishing Group UK
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Language
English
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Publisher
London: Nature Publishing Group UK
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Contents
The main driver of osteoporosis is an imbalance between bone resorption and formation. The pathogenesis of osteoporosis has also been connected to genetic alterations in key osteogenic factors and dysfunction of bone marrow mesenchymal stem/stromal cells (BM-MSCs). Tks4 (encoded by the
Sh3pxd2b
gene) is a scaffold protein involved in podosome...
Alternative Titles
Full title
Significance of the Tks4 scaffold protein in bone tissue homeostasis
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TN_cdi_doaj_primary_oai_doaj_org_article_96550bcba65a4bb08c3d5a75f608f18c
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_96550bcba65a4bb08c3d5a75f608f18c
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ISSN
2045-2322
E-ISSN
2045-2322
DOI
10.1038/s41598-019-42250-6
