Taxanes and platinum derivatives impair Schwann cells via distinct mechanisms
Taxanes and platinum derivatives impair Schwann cells via distinct mechanisms
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London: Nature Publishing Group UK
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English
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London: Nature Publishing Group UK
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Impairment of peripheral neurons by anti-cancer agents, including taxanes and platinum derivatives, has been considered to be a major cause of chemotherapy-induced peripheral neuropathy (CIPN), however, the precise underlying mechanisms are not fully understood. Here, we examined the direct effects of anti-cancer agents on Schwann cells. Exposure o...
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Taxanes and platinum derivatives impair Schwann cells via distinct mechanisms
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TN_cdi_doaj_primary_oai_doaj_org_article_96a74b95e0a94d778ade5e72e0779709
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_96a74b95e0a94d778ade5e72e0779709
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2045-2322
E-ISSN
2045-2322
DOI
10.1038/s41598-017-05784-1