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Taxanes and platinum derivatives impair Schwann cells via distinct mechanisms

Taxanes and platinum derivatives impair Schwann cells via distinct mechanisms

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_96a74b95e0a94d778ade5e72e0779709

Taxanes and platinum derivatives impair Schwann cells via distinct mechanisms

About this item

Full title

Taxanes and platinum derivatives impair Schwann cells via distinct mechanisms

Publisher

London: Nature Publishing Group UK

Journal title

Scientific reports, 2017-07, Vol.7 (1), p.5947-14, Article 5947

Language

English

Formats

Publication information

Publisher

London: Nature Publishing Group UK

More information

Scope and Contents

Contents

Impairment of peripheral neurons by anti-cancer agents, including taxanes and platinum derivatives, has been considered to be a major cause of chemotherapy-induced peripheral neuropathy (CIPN), however, the precise underlying mechanisms are not fully understood. Here, we examined the direct effects of anti-cancer agents on Schwann cells. Exposure o...

Alternative Titles

Full title

Taxanes and platinum derivatives impair Schwann cells via distinct mechanisms

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_doaj_primary_oai_doaj_org_article_96a74b95e0a94d778ade5e72e0779709

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_96a74b95e0a94d778ade5e72e0779709

Other Identifiers

ISSN

2045-2322

E-ISSN

2045-2322

DOI

10.1038/s41598-017-05784-1

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