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Mitochondrial ATP fuels ABC transporter-mediated drug efflux in cancer chemoresistance

Mitochondrial ATP fuels ABC transporter-mediated drug efflux in cancer chemoresistance

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_96cc5e262fc1481b86eceff834f1a9ce

Mitochondrial ATP fuels ABC transporter-mediated drug efflux in cancer chemoresistance

About this item

Full title

Mitochondrial ATP fuels ABC transporter-mediated drug efflux in cancer chemoresistance

Publisher

London: Nature Publishing Group UK

Journal title

Nature communications, 2021-05, Vol.12 (1), p.2804-19, Article 2804

Language

English

Formats

Publication information

Publisher

London: Nature Publishing Group UK

More information

Scope and Contents

Contents

Chemotherapy remains the standard of care for most cancers worldwide, however development of chemoresistance due to the presence of the drug-effluxing ATP binding cassette (ABC) transporters remains a significant problem. The development of safe and effective means to overcome chemoresistance is critical for achieving durable remissions in many can...

Alternative Titles

Full title

Mitochondrial ATP fuels ABC transporter-mediated drug efflux in cancer chemoresistance

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_doaj_primary_oai_doaj_org_article_96cc5e262fc1481b86eceff834f1a9ce

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_96cc5e262fc1481b86eceff834f1a9ce

Other Identifiers

ISSN

2041-1723

E-ISSN

2041-1723

DOI

10.1038/s41467-021-23071-6

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