CTLs heterogeneity and plasticity: implications for cancer immunotherapy
CTLs heterogeneity and plasticity: implications for cancer immunotherapy
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Author / Creator
Peng, Shengkun , Lin, Anqi , Jiang, Aimin , Zhang, Cangang , Zhang, Jian , Cheng, Quan , Luo, Peng and Bai, Yifeng
Publisher
England: BioMed Central Ltd
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Language
English
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Publisher
England: BioMed Central Ltd
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Scope and Contents
Contents
Cytotoxic T lymphocytes (CTLs) play critical antitumor roles, encompassing diverse subsets including CD4+, NK, and γδ T cells beyond conventional CD8+ CTLs. However, definitive CTLs biomarkers remain elusive, as cytotoxicity-molecule expression does not necessarily confer cytotoxic capacity. CTLs differentiation involves transcriptional regulation...
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Full title
CTLs heterogeneity and plasticity: implications for cancer immunotherapy
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TN_cdi_doaj_primary_oai_doaj_org_article_96dffe7c77344b3a81f5b751168894a0
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_96dffe7c77344b3a81f5b751168894a0
Other Identifiers
ISSN
1476-4598
E-ISSN
1476-4598
DOI
10.1186/s12943-024-01972-6