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CTLs heterogeneity and plasticity: implications for cancer immunotherapy

CTLs heterogeneity and plasticity: implications for cancer immunotherapy

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_96dffe7c77344b3a81f5b751168894a0

CTLs heterogeneity and plasticity: implications for cancer immunotherapy

About this item

Full title

CTLs heterogeneity and plasticity: implications for cancer immunotherapy

Publisher

England: BioMed Central Ltd

Journal title

Molecular cancer, 2024-03, Vol.23 (1), p.58-58, Article 58

Language

English

Formats

Publication information

Publisher

England: BioMed Central Ltd

More information

Scope and Contents

Contents

Cytotoxic T lymphocytes (CTLs) play critical antitumor roles, encompassing diverse subsets including CD4+, NK, and γδ T cells beyond conventional CD8+ CTLs. However, definitive CTLs biomarkers remain elusive, as cytotoxicity-molecule expression does not necessarily confer cytotoxic capacity. CTLs differentiation involves transcriptional regulation...

Alternative Titles

Full title

CTLs heterogeneity and plasticity: implications for cancer immunotherapy

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_doaj_primary_oai_doaj_org_article_96dffe7c77344b3a81f5b751168894a0

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_96dffe7c77344b3a81f5b751168894a0

Other Identifiers

ISSN

1476-4598

E-ISSN

1476-4598

DOI

10.1186/s12943-024-01972-6

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