Single-cell expression quantitative trait loci (eQTL) analysis of SLE-risk loci in lupus patient mon...
Single-cell expression quantitative trait loci (eQTL) analysis of SLE-risk loci in lupus patient monocytes
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Author / Creator
Ghodke-Puranik, Yogita , Jin, Zhongbo , Zimmerman, Kip D. , Ainsworth, Hannah C. , Fan, Wei , Jensen, Mark A. , Dorschner, Jessica M. , Vsetecka, Danielle M. , Amin, Shreyasee , Makol, Ashima , Ernste, Floranne , Osborn, Thomas , Moder, Kevin , Chowdhary, Vaidehi , Langefeld, Carl D. and Niewold, Timothy B.
Publisher
England: BioMed Central Ltd
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Language
English
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Publisher
England: BioMed Central Ltd
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Contents
We performed expression quantitative trait locus (eQTL) analysis in single classical (CL) and non-classical (NCL) monocytes from patients with systemic lupus erythematosus (SLE) to quantify the impact of well-established genetic risk alleles on transcription at single-cell resolution.
Single-cell gene expression was quantified using qPCR in puri...
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Full title
Single-cell expression quantitative trait loci (eQTL) analysis of SLE-risk loci in lupus patient monocytes
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TN_cdi_doaj_primary_oai_doaj_org_article_96e352fc33f345cd81032036828010a0
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_96e352fc33f345cd81032036828010a0
Other Identifiers
ISSN
1478-6362,1478-6354
E-ISSN
1478-6362
DOI
10.1186/s13075-021-02660-2
