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Erythropoietin re-wires cognition-associated transcriptional networks

Erythropoietin re-wires cognition-associated transcriptional networks

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_96efba9a694c49e598c5b30a2073b0e7

Erythropoietin re-wires cognition-associated transcriptional networks

About this item

Full title

Erythropoietin re-wires cognition-associated transcriptional networks

Publisher

London: Nature Publishing Group UK

Journal title

Nature communications, 2023-08, Vol.14 (1), p.4777-4777, Article 4777

Language

English

Formats

Publication information

Publisher

London: Nature Publishing Group UK

More information

Scope and Contents

Contents

Recombinant human erythropoietin (rhEPO) has potent procognitive effects, likely hematopoiesis-independent, but underlying mechanisms and physiological role of brain-expressed EPO remained obscure. Here, we provide transcriptional hippocampal profiling of male mice treated with rhEPO. Based on ~108,000 single nuclei, we unmask multiple pyramidal li...

Alternative Titles

Full title

Erythropoietin re-wires cognition-associated transcriptional networks

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_doaj_primary_oai_doaj_org_article_96efba9a694c49e598c5b30a2073b0e7

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_96efba9a694c49e598c5b30a2073b0e7

Other Identifiers

ISSN

2041-1723

E-ISSN

2041-1723

DOI

10.1038/s41467-023-40332-8

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