Accumbens dopamine D2 receptors increase motivation by decreasing inhibitory transmission to the ven...
Accumbens dopamine D2 receptors increase motivation by decreasing inhibitory transmission to the ventral pallidum
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London: Nature Publishing Group UK
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English
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London: Nature Publishing Group UK
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Dopamine D2 receptors (D2Rs) in the nucleus accumbens (NAc) regulate motivated behavior, but the underlying neurobiological mechanisms remain unresolved. Here, we show that selective upregulation of D2Rs in the indirect pathway of the adult NAc enhances the willingness to work for food. Mechanistic studies in brain slices reveal that D2R upregulati...
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Accumbens dopamine D2 receptors increase motivation by decreasing inhibitory transmission to the ventral pallidum
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TN_cdi_doaj_primary_oai_doaj_org_article_9716d06b79b041318d69d2b9867976d1
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_9716d06b79b041318d69d2b9867976d1
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ISSN
2041-1723
E-ISSN
2041-1723
DOI
10.1038/s41467-018-03272-2
