Gene editing for latent herpes simplex virus infection reduces viral load and shedding in vivo
Gene editing for latent herpes simplex virus infection reduces viral load and shedding in vivo
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Publisher
London: Nature Publishing Group UK
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Language
English
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London: Nature Publishing Group UK
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Contents
Anti-HSV therapies are only suppressive because they do not eliminate latent HSV present in ganglionic neurons, the source of recurrent disease. We have developed a potentially curative approach against HSV infection, based on gene editing using HSV-specific meganucleases delivered by adeno-associated virus (AAV) vectors. Gene editing performed wit...
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Full title
Gene editing for latent herpes simplex virus infection reduces viral load and shedding in vivo
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TN_cdi_doaj_primary_oai_doaj_org_article_9723e7ae8e8b4b0fabbaa81b521d59db
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_9723e7ae8e8b4b0fabbaa81b521d59db
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ISSN
2041-1723
E-ISSN
2041-1723
DOI
10.1038/s41467-024-47940-y
