The Expression Regulation and Cancer-Promoting Roles of RACGAP1
The Expression Regulation and Cancer-Promoting Roles of RACGAP1
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Author / Creator
Lin, Jiacheng , Zhu, Yuhao , Lin, Zhaoping , Yu, Jindong , Lin, Xiaobing , Lai, Weiyuan , Tong, Beibei , Xu, Liyan , Li, Enmin and Long, Lin
Publisher
Switzerland: MDPI AG
Journal title
Language
English
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Publication information
Publisher
Switzerland: MDPI AG
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Scope and Contents
Contents
RACGAP1 is a Rho-GTPase-activating protein originally discovered in male germ cells to inactivate Rac, RhoA and Cdc42 from the GTP-bound form to the GDP-bound form. GAP has traditionally been known as a tumor suppressor. However, studies increasingly suggest that overexpressed RACGAP1 activates Rac and RhoA in multiple cancers to mediate downstream...
Alternative Titles
Full title
The Expression Regulation and Cancer-Promoting Roles of RACGAP1
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Record Identifier
TN_cdi_doaj_primary_oai_doaj_org_article_9725121417fd41d8831812e6fb1844b9
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_9725121417fd41d8831812e6fb1844b9
Other Identifiers
ISSN
2218-273X
E-ISSN
2218-273X
DOI
10.3390/biom15010003
