Epithelial tumor suppressor ELF3 is a lineage-specific amplified oncogene in lung adenocarcinoma
Epithelial tumor suppressor ELF3 is a lineage-specific amplified oncogene in lung adenocarcinoma
About this item
Full title
Author / Creator
Enfield, Katey S. S. , Marshall, Erin A. , Anderson, Christine , Ng, Kevin W. , Rahmati, Sara , Xu, Zhaolin , Fuller, Megan , Milne, Katy , Lu, Daniel , Shi, Rocky , Rowbotham, David A. , Becker-Santos, Daiana D. , Johnson, Fraser D. , English, John C. , MacAulay, Calum E. , Lam, Stephen , Lockwood, William W. , Chari, Raj , Karsan, Aly , Jurisica, Igor and Lam, Wan L.
Publisher
London: Nature Publishing Group UK
Journal title
Language
English
Formats
Publication information
Publisher
London: Nature Publishing Group UK
Subjects
More information
Scope and Contents
Contents
Gene function in cancer is often cell type-specific. The epithelial cell-specific transcription factor ELF3 is a documented tumor suppressor in many epithelial tumors yet displays oncogenic properties in others. Here, we show that ELF3 is an oncogene in the adenocarcinoma subtype of lung cancer (LUAD), providing genetic, functional, and clinical ev...
Alternative Titles
Full title
Epithelial tumor suppressor ELF3 is a lineage-specific amplified oncogene in lung adenocarcinoma
Authors, Artists and Contributors
Author / Creator
Marshall, Erin A.
Anderson, Christine
Ng, Kevin W.
Rahmati, Sara
Xu, Zhaolin
Fuller, Megan
Milne, Katy
Lu, Daniel
Shi, Rocky
Rowbotham, David A.
Becker-Santos, Daiana D.
Johnson, Fraser D.
English, John C.
MacAulay, Calum E.
Lam, Stephen
Lockwood, William W.
Chari, Raj
Karsan, Aly
Jurisica, Igor
Lam, Wan L.
Identifiers
Primary Identifiers
Record Identifier
TN_cdi_doaj_primary_oai_doaj_org_article_97564470fd144a769823f07282f004b8
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_97564470fd144a769823f07282f004b8
Other Identifiers
ISSN
2041-1723
E-ISSN
2041-1723
DOI
10.1038/s41467-019-13295-y
