Toward an integrated map of genetic interactions in cancer cells
Toward an integrated map of genetic interactions in cancer cells
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London: Nature Publishing Group UK
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English
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London: Nature Publishing Group UK
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Contents
Cancer genomes often harbor hundreds of molecular aberrations. Such genetic variants can be drivers or passengers of tumorigenesis and create vulnerabilities for potential therapeutic exploitation. To identify genotype‐dependent vulnerabilities, forward genetic screens in different genetic backgrounds have been conducted. We devised MINGLE, a compu...
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Toward an integrated map of genetic interactions in cancer cells
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TN_cdi_doaj_primary_oai_doaj_org_article_976451cedcc74a589433ae90e6e6e00f
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_976451cedcc74a589433ae90e6e6e00f
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ISSN
1744-4292
E-ISSN
1744-4292
DOI
10.15252/msb.20177656