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Toward an integrated map of genetic interactions in cancer cells

Toward an integrated map of genetic interactions in cancer cells

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_976451cedcc74a589433ae90e6e6e00f

Toward an integrated map of genetic interactions in cancer cells

About this item

Full title

Toward an integrated map of genetic interactions in cancer cells

Publisher

London: Nature Publishing Group UK

Journal title

Molecular systems biology, 2018-02, Vol.14 (2), p.e7656-n/a

Language

English

Formats

Publication information

Publisher

London: Nature Publishing Group UK

More information

Scope and Contents

Contents

Cancer genomes often harbor hundreds of molecular aberrations. Such genetic variants can be drivers or passengers of tumorigenesis and create vulnerabilities for potential therapeutic exploitation. To identify genotype‐dependent vulnerabilities, forward genetic screens in different genetic backgrounds have been conducted. We devised MINGLE, a compu...

Alternative Titles

Full title

Toward an integrated map of genetic interactions in cancer cells

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_doaj_primary_oai_doaj_org_article_976451cedcc74a589433ae90e6e6e00f

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_976451cedcc74a589433ae90e6e6e00f

Other Identifiers

ISSN

1744-4292

E-ISSN

1744-4292

DOI

10.15252/msb.20177656

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