Toward an integrated map of genetic interactions in cancer cells
Toward an integrated map of genetic interactions in cancer cells
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Publisher
London: Nature Publishing Group UK
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Language
English
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Publisher
London: Nature Publishing Group UK
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Contents
Cancer genomes often harbor hundreds of molecular aberrations. Such genetic variants can be drivers or passengers of tumorigenesis and create vulnerabilities for potential therapeutic exploitation. To identify genotype‐dependent vulnerabilities, forward genetic screens in different genetic backgrounds have been conducted. We devised MINGLE, a compu...
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Full title
Toward an integrated map of genetic interactions in cancer cells
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TN_cdi_doaj_primary_oai_doaj_org_article_976451cedcc74a589433ae90e6e6e00f
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_976451cedcc74a589433ae90e6e6e00f
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ISSN
1744-4292
E-ISSN
1744-4292
DOI
10.15252/msb.20177656
