Extracellular vesicles and exosomes generated from cystic renal epithelial cells promote cyst growth...
Extracellular vesicles and exosomes generated from cystic renal epithelial cells promote cyst growth in autosomal dominant polycystic kidney disease
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Publisher
London: Nature Publishing Group UK
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Language
English
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Publisher
London: Nature Publishing Group UK
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Scope and Contents
Contents
Autosomal dominant polycystic kidney disease (ADPKD) is caused by germline mutations of
PKD1
or
PKD2
on one allele and a somatic mutation inactivating the remaining normal allele. However, if and how null ADPKD gene renal epithelial cells affect the biology and function of neighboring cells, including heterozygous renal epithelial cells...
Alternative Titles
Full title
Extracellular vesicles and exosomes generated from cystic renal epithelial cells promote cyst growth in autosomal dominant polycystic kidney disease
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TN_cdi_doaj_primary_oai_doaj_org_article_978a2efe63ee4aecbb0e7b5a78ffde38
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_978a2efe63ee4aecbb0e7b5a78ffde38
Other Identifiers
ISSN
2041-1723
E-ISSN
2041-1723
DOI
10.1038/s41467-021-24799-x
