PP2A in LepR+ mesenchymal stem cells contributes to embryonic and postnatal endochondral ossificatio...
PP2A in LepR+ mesenchymal stem cells contributes to embryonic and postnatal endochondral ossification through Runx2 dephosphorylation
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London: Nature Publishing Group UK
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English
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London: Nature Publishing Group UK
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It has not been well studied which cells and related mechanisms contribute to endochondral ossification. Here, we fate mapped the leptin receptor-expressing (LepR
+
) mesenchymal stem cells (MSCs) in different embryonic and adult extremities using
Lepr-cre; tdTomato
mice and investigated the underling mechanism using
Lepr-cre; Ppp2r1...
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Full title
PP2A in LepR+ mesenchymal stem cells contributes to embryonic and postnatal endochondral ossification through Runx2 dephosphorylation
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TN_cdi_doaj_primary_oai_doaj_org_article_978e00f7f57c44eb88f999b670dfc8e4
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_978e00f7f57c44eb88f999b670dfc8e4
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ISSN
2399-3642
E-ISSN
2399-3642
DOI
10.1038/s42003-021-02175-1
