Reducing the shock factor with new anti-epilepsy drugs
Reducing the shock factor with new anti-epilepsy drugs
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Publisher
Cambridge: The Company of Biologists Ltd
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Language
English
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Publisher
Cambridge: The Company of Biologists Ltd
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Contents
The authors identified a new compound, 4-tert-butyl-benzaldehyde (4-TBB), which could increase expression and stability of PUM in Drosophila and mice, and had physiochemical properties compatible with clinical use. The authors then identified RAB216, a more-potent analogue of 4-TBB, which also increased PUM expression, and induced anticonvulsant ac...
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Full title
Reducing the shock factor with new anti-epilepsy drugs
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TN_cdi_doaj_primary_oai_doaj_org_article_9790e3318912448983d4fbfaa608a6a5
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_9790e3318912448983d4fbfaa608a6a5
Other Identifiers
ISSN
1754-8403
E-ISSN
1754-8411
DOI
10.1242/dmm.049886
