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Neuronal Excitation Induces Tau Protein Dephosphorylation via Protein Phosphatase 1 Activation to Pr...

Neuronal Excitation Induces Tau Protein Dephosphorylation via Protein Phosphatase 1 Activation to Pr...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_97c776c3d76145dc84d82e02909c6183

Neuronal Excitation Induces Tau Protein Dephosphorylation via Protein Phosphatase 1 Activation to Promote Its Binding with Stable Microtubules

About this item

Full title

Neuronal Excitation Induces Tau Protein Dephosphorylation via Protein Phosphatase 1 Activation to Promote Its Binding with Stable Microtubules

Publisher

Switzerland: MDPI AG

Journal title

Neurology International, 2024-06, Vol.16 (3), p.653-662

Language

English

Formats

Publication information

Publisher

Switzerland: MDPI AG

More information

Scope and Contents

Contents

The tau protein is a microtubule-associated protein that promotes microtubule stabilization. The phosphorylation of the tau protein has been linked to its dissociation from microtubules. Here, we examined the relationship between neuronal depolarization activity and tau protein phosphorylation by employing model systems in culture as well as in viv...

Alternative Titles

Full title

Neuronal Excitation Induces Tau Protein Dephosphorylation via Protein Phosphatase 1 Activation to Promote Its Binding with Stable Microtubules

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_doaj_primary_oai_doaj_org_article_97c776c3d76145dc84d82e02909c6183

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_97c776c3d76145dc84d82e02909c6183

Other Identifiers

ISSN

2035-8377,2035-8385

E-ISSN

2035-8377

DOI

10.3390/neurolint16030049

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