IgG4:IgG RNA ratio differentiates active disease from remission in granulomatosis with polyangiitis:...
IgG4:IgG RNA ratio differentiates active disease from remission in granulomatosis with polyangiitis: a new disease activity marker? A cross-sectional and longitudinal study
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England: BioMed Central Ltd
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English
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England: BioMed Central Ltd
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An important limitation in granulomatosis with polyangiitis (GPA) is the lack of disease activity markers. Immunoglobulin G4-positive (IgG4
) B cells and plasma cells are implicated in the pathogenesis of GPA. We hypothesized that the presence of these cells in peripheral blood could serve as disease activity parameter in GPA.
We included 35...
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IgG4:IgG RNA ratio differentiates active disease from remission in granulomatosis with polyangiitis: a new disease activity marker? A cross-sectional and longitudinal study
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TN_cdi_doaj_primary_oai_doaj_org_article_97fc3ae57f064f7ca6b4cc620dcc70d8
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_97fc3ae57f064f7ca6b4cc620dcc70d8
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ISSN
1478-6362,1478-6354
E-ISSN
1478-6362
DOI
10.1186/s13075-018-1806-6
