A neonatal gnotobiotic pig model of human enterovirus 71 infection and associated immune responses
A neonatal gnotobiotic pig model of human enterovirus 71 infection and associated immune responses
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Author / Creator
Yang, Xingdong , Li, Guohua , Wen, Ke , Bui, Tammy , Liu, Fangning , Kocher, Jacob , Jortner, Bernard S , Vonck, Marlice , Pelzer, Kevin , Deng, Jie , Zhu, Runan , Li, Yuyun , Qian, Yuan and Yuan, Lijuan
Publisher
United States: Taylor & Francis Ltd
Journal title
Language
English
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Publication information
Publisher
United States: Taylor & Francis Ltd
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Scope and Contents
Contents
Vaccine development and pathogenesis studies for human enterovirus 71 are limited by a lack of suitable animal models. Here, we report the development of a novel neonatal gnotobiotic pig model using the non-pig-adapted neurovirulent human enterovirus 71 strain BJ110, which has a C4 genotype. Porcine small intestinal epithelial cells, peripheral blo...
Alternative Titles
Full title
A neonatal gnotobiotic pig model of human enterovirus 71 infection and associated immune responses
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Record Identifier
TN_cdi_doaj_primary_oai_doaj_org_article_983f0d9d45d54e82839649d0571d08e3
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_983f0d9d45d54e82839649d0571d08e3
Other Identifiers
ISSN
2222-1751
E-ISSN
2222-1751
DOI
10.1038/emi.2014.35
