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Chromodomain mutation in S. pombe Kat5/Mst1 affects centromere dynamics and DNA repair

Chromodomain mutation in S. pombe Kat5/Mst1 affects centromere dynamics and DNA repair

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_9848733b72814022a7005bca2077b588

Chromodomain mutation in S. pombe Kat5/Mst1 affects centromere dynamics and DNA repair

About this item

Full title

Chromodomain mutation in S. pombe Kat5/Mst1 affects centromere dynamics and DNA repair

Publisher

United States: Public Library of Science

Journal title

PloS one, 2024-04, Vol.19 (4), p.e0300732

Language

English

Formats

Publication information

Publisher

United States: Public Library of Science

More information

Scope and Contents

Contents

KAT5 (S. pombe Mst1, human TIP60) is a MYST family histone acetyltransferase conserved from yeast to humans that is involved in multiple cellular activities. This family is characterized in part by containing a chromodomain, a motif associated with binding methylated histones. We show that a chromodomain mutation in the S. pombe Kat5, mst1-W66R, ha...

Alternative Titles

Full title

Chromodomain mutation in S. pombe Kat5/Mst1 affects centromere dynamics and DNA repair

Authors, Artists and Contributors

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_doaj_primary_oai_doaj_org_article_9848733b72814022a7005bca2077b588

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_9848733b72814022a7005bca2077b588

Other Identifiers

ISSN

1932-6203

E-ISSN

1932-6203

DOI

10.1371/journal.pone.0300732

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