Mitochondrial Calcium Transporters Mediate Sensitivity to Noise-Induced Losses of Hair Cells and Coc...
Mitochondrial Calcium Transporters Mediate Sensitivity to Noise-Induced Losses of Hair Cells and Cochlear Synapses
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Author / Creator
Wang, Xianren , Zhu, Yuanping , Long, Haishan , Pan, Song , Xiong, Hao , Fang, Qiaojun , Hill, Kayla , Lai, Ruosha , Yuan, Hu and Sha, Su-Hua
Publisher
Switzerland: Frontiers Research Foundation
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Language
English
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Publisher
Switzerland: Frontiers Research Foundation
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Contents
Mitochondria modulate cellular calcium homeostasis by the combined action of the mitochondrial calcium uniporter (MCU), a selective calcium entry channel, and the sodium calcium exchanger (NCLX), which extrudes calcium from mitochondria. In this study, we investigated MCU and NCLX in noise-induced hearing loss (NIHL) using adult CBA/J mice and nois...
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Full title
Mitochondrial Calcium Transporters Mediate Sensitivity to Noise-Induced Losses of Hair Cells and Cochlear Synapses
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TN_cdi_doaj_primary_oai_doaj_org_article_989ffd126b7c45f591bf9524b5de2699
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_989ffd126b7c45f591bf9524b5de2699
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ISSN
1662-5099
E-ISSN
1662-5099
DOI
10.3389/fnmol.2018.00469