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The ubiquitin ligase c-CBL is expressed in undifferentiated marmoset monkey pluripotent stem cells b...

The ubiquitin ligase c-CBL is expressed in undifferentiated marmoset monkey pluripotent stem cells b...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_98b1bde1478644808ada660e5b44cc80

The ubiquitin ligase c-CBL is expressed in undifferentiated marmoset monkey pluripotent stem cells but is not a general stem cell marker

About this item

Full title

The ubiquitin ligase c-CBL is expressed in undifferentiated marmoset monkey pluripotent stem cells but is not a general stem cell marker

Publisher

Germany: Copernicus GmbH

Journal title

Primate Biology, 2017, Vol.4 (2), p.231-240

Language

English

Formats

Publication information

Publisher

Germany: Copernicus GmbH

More information

Scope and Contents

Contents

The protein c-CBL is a ubiquitin ligase. It catalyzes the last step of the transfer of ubiquitin to target proteins. Upon completion of polyubiquitination, the target proteins are degraded. Clinically, it is important that c-CBL is mutated in a subset of patients who develop myeloid malignancies, which are diseases of the hematopoietic stem or prog...

Alternative Titles

Full title

The ubiquitin ligase c-CBL is expressed in undifferentiated marmoset monkey pluripotent stem cells but is not a general stem cell marker

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_doaj_primary_oai_doaj_org_article_98b1bde1478644808ada660e5b44cc80

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_98b1bde1478644808ada660e5b44cc80

Other Identifiers

ISSN

2363-4715,2363-4707

E-ISSN

2363-4715

DOI

10.5194/pb-4-231-2017

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