Matrix mechanical plasticity regulates cancer cell migration through confining microenvironments
Matrix mechanical plasticity regulates cancer cell migration through confining microenvironments
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London: Nature Publishing Group UK
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English
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London: Nature Publishing Group UK
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Studies of cancer cell migration have found two modes: one that is protease-independent, requiring micron-sized pores or channels for cells to squeeze through, and one that is protease-dependent, relevant for confining nanoporous matrices such as basement membranes (BMs). However, many extracellular matrices exhibit viscoelasticity and mechanical p...
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Matrix mechanical plasticity regulates cancer cell migration through confining microenvironments
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TN_cdi_doaj_primary_oai_doaj_org_article_98c929b92b67496b9f803a21d27ece3c
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_98c929b92b67496b9f803a21d27ece3c
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ISSN
2041-1723
E-ISSN
2041-1723
DOI
10.1038/s41467-018-06641-z