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Matrix mechanical plasticity regulates cancer cell migration through confining microenvironments

Matrix mechanical plasticity regulates cancer cell migration through confining microenvironments

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_98c929b92b67496b9f803a21d27ece3c

Matrix mechanical plasticity regulates cancer cell migration through confining microenvironments

About this item

Full title

Matrix mechanical plasticity regulates cancer cell migration through confining microenvironments

Publisher

London: Nature Publishing Group UK

Journal title

Nature communications, 2018-10, Vol.9 (1), p.4144-13, Article 4144

Language

English

Formats

Publication information

Publisher

London: Nature Publishing Group UK

More information

Scope and Contents

Contents

Studies of cancer cell migration have found two modes: one that is protease-independent, requiring micron-sized pores or channels for cells to squeeze through, and one that is protease-dependent, relevant for confining nanoporous matrices such as basement membranes (BMs). However, many extracellular matrices exhibit viscoelasticity and mechanical p...

Alternative Titles

Full title

Matrix mechanical plasticity regulates cancer cell migration through confining microenvironments

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_doaj_primary_oai_doaj_org_article_98c929b92b67496b9f803a21d27ece3c

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_98c929b92b67496b9f803a21d27ece3c

Other Identifiers

ISSN

2041-1723

E-ISSN

2041-1723

DOI

10.1038/s41467-018-06641-z

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