128 KIR haplotype can inform donor selection production of allogeneic memory-like CAR NK cells for c...
128 KIR haplotype can inform donor selection production of allogeneic memory-like CAR NK cells for clinical application
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London: BMJ Publishing Group Ltd
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English
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London: BMJ Publishing Group Ltd
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BackgroundNK cells expanded on membrane-bound (mb) IL-15 and 41BBL expressing K562 stimulatory cells (NKSTIM) for clinical use can be genetically modified to express activating chimeric receptors.1 2 3 NK cells activated in the presence of IL-12, IL-15 and IL-18 develop cytokine induced memory-like (CIML) phenotype and function; these cells have sh...
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128 KIR haplotype can inform donor selection production of allogeneic memory-like CAR NK cells for clinical application
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TN_cdi_doaj_primary_oai_doaj_org_article_991fa3acc4f147c0b5344e80fea27c3b
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_991fa3acc4f147c0b5344e80fea27c3b
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E-ISSN
2051-1426
DOI
10.1136/jitc-2021-SITC2021.128
