Spinal neural tube closure depends on regulation of surface ectoderm identity and biomechanics by Gr...
Spinal neural tube closure depends on regulation of surface ectoderm identity and biomechanics by Grhl2
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London: Nature Publishing Group UK
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Language
English
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Publisher
London: Nature Publishing Group UK
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Lack or excess expression of the surface ectoderm-expressed transcription factor Grainyhead-like2 (Grhl2), each prevent spinal neural tube closure. Here we investigate the causative mechanisms and find reciprocal dysregulation of epithelial genes, cell junction components and actomyosin properties in Grhl2 null and over-expressing embryos. Grhl2 nu...
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Spinal neural tube closure depends on regulation of surface ectoderm identity and biomechanics by Grhl2
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TN_cdi_doaj_primary_oai_doaj_org_article_997301dd14a44cfe8d45c82ba65c8e2b
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_997301dd14a44cfe8d45c82ba65c8e2b
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ISSN
2041-1723
E-ISSN
2041-1723
DOI
10.1038/s41467-019-10164-6
