Deep flanking sequence engineering for efficient promoter design using DeepSEED
Deep flanking sequence engineering for efficient promoter design using DeepSEED
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Author / Creator
Zhang, Pengcheng , Wang, Haochen , Xu, Hanwen , Wei, Lei , Liu, Liyang , Hu, Zhirui and Wang, Xiaowo
Publisher
London: Nature Publishing Group UK
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Language
English
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Publisher
London: Nature Publishing Group UK
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Contents
Designing promoters with desirable properties is essential in synthetic biology. Human experts are skilled at identifying strong explicit patterns in small samples, while deep learning models excel at detecting implicit weak patterns in large datasets. Biologists have described the sequence patterns of promoters via transcription factor binding sit...
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Full title
Deep flanking sequence engineering for efficient promoter design using DeepSEED
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TN_cdi_doaj_primary_oai_doaj_org_article_997de74c05aa4d88b09ec82d5559fe75
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_997de74c05aa4d88b09ec82d5559fe75
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ISSN
2041-1723
E-ISSN
2041-1723
DOI
10.1038/s41467-023-41899-y